Basic Changes in Protein Metabolism during Stress.
ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FREDERICK MD
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The wasting of body proteins during a stressful illness is the decreased synthesis and increased degradation of peripheral tissue such as skeletal muscle. The amino acids released from these tissues are used as an energy source by the peripheral tissue, substrate for gluconeogenesis, production of proteins associated with host defense against the stressful illness, tissue repair and abnormal growth, and synthesis of obligatory proteins. This results in a rapid depletion of protein in peripheral tissue and a decreased supply of amino acids to meet the metabolic insult of the stressful illness.
- Stress Physiology