Cardiovascular, Renal and Respiratory Effects of High Intensity, Intermediate Duration, Low Frequency Vibration.
Interim rept. no. 3, 1 Jul 75-30 Jun 76,
OHIO STATE UNIV COLUMBUS DEPT OF AERONAUTICAL AND ASTRONAUTICAL ENGINEERING
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A research program on the influence of high intensity, intermediate duration, low-frequency wholebody vibration on the cardiovascular, renal and respiratory systems is described. During the period 1 July 1975 to 30 June 1976, emphasis was placed on the in vitro study of the transport of C14-4-cholesterol between blood and the arterial wall in the presence of oscillatory flow conditions. In addition, a previous in vivo investigation of I131-albumin transport in the aorta was extended to include measurements during vibration at 6 and 14 Hz. These in vivo studies indicate an enhancement of albumin uptake during vibration in the dog aorta. The in vivo data are consistent with in vitro data and the concept of a shear-dependent transport process. Continuing in vivo studies are being carried out to measure aortic pressure and velocity waveforms.
- Stress Physiology