Accession Number:

ADA036232

Title:

Chemical Protection of the Mouse against Leukemia Induction by X-Rays

Descriptive Note:

Corporate Author:

SCHOOL OF AVIATION MEDICINE RANDOLPH AFB TX

Personal Author(s):

Report Date:

1959-04-01

Pagination or Media Count:

7.0

Abstract:

Administration of mercaptoethylguanidine shortly before a single whole-body exposure to 150 or 300 r of x-rays inhibits the induction of granulocytic leukemia and prevents the induction of thymic lymphoma in RF mice. Mice treated with the drug also exhibit less shortening of the life span by radiation than do untreated controls.

Subject Categories:

  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE