Monkeys as Hosts of Human Malaria and Other Pathogens.
Final rept. 1 Sep 71-31 Dec 75,
GORGAS MEMORIAL LAB BALBOA HEIGHTS CANAL ZONE
Pagination or Media Count:
A passage line of the Panama II strain of Plasmodium falciparum was produced in Alouatta villosa trabeata and viability of the Vietnam-Oak Knoll was confirmed after 3 years of cryopreservation. Also for the first time, intact Ateles fusciceps and A. geoffroyi were infected with Achiote P. vivax, including Panamanian and Guatemalan subspecies of the latter Ateles. Plasmodium simium developed in unaltered subjects of all 7 species of Panamanian monkeys, 5 of these new experimental hosts. Ten and 28 of monkeys surveyed evidenced Trypanosoma 4 species and Dipetalonema 3 species. Colony mating and parturition was recorded in Cebus capucinus, Saguinus geoffroyi, A. fusciceps, and A. geoffroyi, with a total of 24 viable births. Data were acquired on the description, life cycle and rearing of poorly known jungle mosquitoes, Anopheles neivai, Chagasia bathana and A. squamifemur. Anopheles albimanus malaria infections were best obtained from sporozoite induced parasitemias of Achiote vivax in splenectomized Aotus trivirgatus. Transmission was effected to A. trivirgatus, S. geoffroyi, Saimiri scuireus and both Ateles spp. exoerythrocytic stages were demonstrated in each of these systems and C. capucinus and C. apella, refractory to the blood phase. Author
- Medicine and Medical Research