Accession Number:

ADA031054

Title:

The Application of Stochastic Approximation Methods to the Bio-Assay Problem.

Descriptive Note:

Technical rept.,

Corporate Author:

CASE WESTERN RESERVE UNIV CLEVELAND OHIO DEPT OF MATHEMATICS AND STATISTICS

Personal Author(s):

Report Date:

1976-08-02

Pagination or Media Count:

21.0

Abstract:

A new general model for the bio-assay problem is introduced. It is shown that when the slope of the dose-response curve and the median effective dose is known, the Robbins-Monro method yields an asymptotically optimal estimation procedure. Adaptive procedures are discussed for the case of unknown slope. Results of Monte Carlo studies are given. Author

Subject Categories:

  • Biochemistry
  • Statistics and Probability

Distribution Statement:

APPROVED FOR PUBLIC RELEASE