The Application of Stochastic Approximation Methods to the Bio-Assay Problem.
CASE WESTERN RESERVE UNIV CLEVELAND OHIO DEPT OF MATHEMATICS AND STATISTICS
Pagination or Media Count:
A new general model for the bio-assay problem is introduced. It is shown that when the slope of the dose-response curve and the median effective dose is known, the Robbins-Monro method yields an asymptotically optimal estimation procedure. Adaptive procedures are discussed for the case of unknown slope. Results of Monte Carlo studies are given. Author
- Statistics and Probability