Accession Number:

ADA030820

Title:

Effects on Blood Pressure and Heart Rate of Selective Shielding of Midline Trunk Structures in Monkeys Exposed to 1000 Rads 60 Co

Descriptive Note:

Topical rept.

Corporate Author:

LOVELACE FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH ALBUQUERQUE NM

Personal Author(s):

Report Date:

1976-06-18

Pagination or Media Count:

21.0

Abstract:

Blood pressure BP and heart rate HR were monitored in three groups of shielded, nonperforming monkeys, and one unshielded control during and after exposure to 1000 rads 60 Co at 150 radmin. A narrow, vertically-oriented lead shield was located over either the dorsal midline vertebral column or laterally just to the left or right of midline in the three shielding groups. Purpose was to determine if selective shielding of underlying structures e.g., spinal cord, autonomic ganglia, heart, spleen, etc. would alter the postradiation hypotensive response. No differential effects of shielding placement on BP or HR were observed, nor did the shielding groups differ from the unshielded. Absence of radiosensitive target organs implies the hypotensive trigger site is diffuse, for example, the peripheral vasculature.

Subject Categories:

  • Radiobiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE