Accession Number:

ADA029935

Title:

Synthesis and Testing of Polymers Susceptible to Degradation by Proteolytic Enzymes

Descriptive Note:

Final rept. 1 Jul 1974-30 Jun 1975

Corporate Author:

CONNECTICUT UNIV STORRS

Personal Author(s):

Report Date:

1975-05-01

Pagination or Media Count:

48.0

Abstract:

This report describes synthesis, biodegradation, and property studies on new materials which have both biodegradability and good physical properties. A copolymer of polycaprolactone blocks, terminated with ethanolamine and linked by diisocyanatohexane, was biodegraded by the enzymes urease and rennin, and also by two fungi. The tensile strength was greater than 10,000 psi, with high ultimate tensile elongation. Plasticized gelatin crosslinked with dilute diisocyanatohexane also has produced fibers with very high biodegradability and good strength. The fibers are drawn before passing them through a bath containing the crosslinking agent. Other polymers of interest which have been found to be biodegradable include a polyester-urea, which is based on polyL- phenyl-alamine, and copolymers based on mandelic acid.

Subject Categories:

  • Biochemistry
  • Polymer Chemistry
  • Plastics
  • Civil Engineering

Distribution Statement:

APPROVED FOR PUBLIC RELEASE