Development of a Synthetic Burn Covering.
DYNATECH R/D CO CAMBRIDGE MASS
Pagination or Media Count:
Thirty-two samples made from PCL napped knitted fabric laminated to PCL film were evaluated in vivo as a synthetic burn covering by applying them to full thickness excision wounds on the backs of rats. The degree of napping proved to be critical with a light nap being optimum. A medium to heavy nap adhered too well so that some of the newly formed tissue was torn from the back of the rat when the covering was removed three days after application. The thickness of the laminates were such that difficulty was experienced in obtaining adherence to the back of the rat without puckers or creases which permitted some air to reach the wound with resulting minor infection and poor adhesion at these points. Otherwise the grafts were well tolerated by the rat.
- Medicine and Medical Research