Immunology of Schistosomiasis.
Final rept. 1 May 70-15 Jul 75,
AMERICAN FOUNDATION FOR BIOLOGICAL RESEARCH ROCKVILLE MD BIOMEDICAL RESEARCH INST
Pagination or Media Count:
The original purpose of this contract was to find a process by which tissue surface antigens might be modified or changed. To accomplish this, a model system was needed in which surface antigen modification was known to occur naturally. Such a system was available in a host-parasite model using rodent hosts and the parasitic blood fluke, Schistosoma mansoni. Invading stages of this schistosome cover their surface with host-like antigens and thus protect themselves against destruction by host antibodies.
- Medicine and Medical Research