Accession Number:

ADA028368

Title:

Immunology of Schistosomiasis.

Descriptive Note:

Final rept. 1 May 70-15 Jul 75,

Corporate Author:

AMERICAN FOUNDATION FOR BIOLOGICAL RESEARCH ROCKVILLE MD BIOMEDICAL RESEARCH INST

Personal Author(s):

Report Date:

1975-07-01

Pagination or Media Count:

14.0

Abstract:

The original purpose of this contract was to find a process by which tissue surface antigens might be modified or changed. To accomplish this, a model system was needed in which surface antigen modification was known to occur naturally. Such a system was available in a host-parasite model using rodent hosts and the parasitic blood fluke, Schistosoma mansoni. Invading stages of this schistosome cover their surface with host-like antigens and thus protect themselves against destruction by host antibodies.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE