Water Content of Stratum Corneum 'In Vivo'.
Annual progress rept. 1 May 75-31 Jan 76,
WASHINGTON UNIV SEATTLE DEPT OF MEDICINE (DERMATOLOGY)
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The authors using a 4-point microelectrode method for studying the relationship between electrical resistivity, water content, electrolyte levels, and water binding in stratum corneum. Resistivity is measured with a microcircuit skin surface probe printed onto a glass substrate. A constant current source drives the outer two electrodes at 1 Hz the potential drop is measured across the inner two electrodes. The device is capable of obtaining accurate surface resistance measurements on two layer materials when the first layer is between 0.1 - 0.4 mm thick on plantar and palmar skin this corresponds to the stratum corneum. Samples of plantar skin have been tested during standardized desorption procedures.
- Medicine and Medical Research