Accession Number:

ADA025362

Title:

Use of Physostigmine by the Intravenous, Intramuscular, and Oral Routes in the Therapy of Anticholinergic Drug Intoxication

Descriptive Note:

Technical rept. Jul 1968-May 1975

Corporate Author:

EDGEWOOD ARSENAL ABERDEEN PROVING GROUND MD

Personal Author(s):

• Sidell, Frederick R.

Report Date:

1976-05-01

Pagination or Media Count:

25.0

Abstract:

Physostigmine was administered by three routes intravenous, intramuscular, and oral to treat intoxication by anticholinergic compounds in man. The drug by all routes of administration is effective. There are several reasons why the intravenous route of administration is not preferable for routine use.

Descriptors:

• *ANTIDOTES
• *BELLADONNA ALKALOIDS
• ATROPINE
• ENLISTED PERSONNEL
• HEART
• PREVENTION
• SCOPOLAMINE
• THERAPY
• TOXICITY

Subject Categories:

• Toxicology
• Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE