Accession Number:

ADA023121

Title:

A Quantitative Assay to Measure Physostigmine in Human Whole Blood.

Descriptive Note:

Technical rept. Jan 73-Jan 75,

Corporate Author:

EDGEWOOD ARSENAL ABERDEEN PROVING GROUND MD

Report Date:

1976-02-01

Pagination or Media Count:

17.0

Abstract:

This report describes a quantitative assay method for measuring physostigmine in human whole blood. Blood samples are maintained at 37 C, and cholinesterase activity is measured periodically. The time required for enzyme reactivation is related to physostigmine concentration. The precision of the method is within or - 4 over a physostigmine concentration range of 0.5 to 5.0 x 10 to the minus 7th power molliter. Author

Subject Categories:

  • Toxicology
  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE