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Evaluation of the Squirrel Monkey (Saimiri sciureus) as an Experimental Animal Model for Dysbaric Osteonecrosis.
NAVAL AEROSPACE MEDICAL RESEARCH LAB PENSACOLA FL
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In an attempt to develop an animal model for dysbaric ostenonecrosis in man, squirrel monkeys were repeatedly exposed to a profile consisting of both hyperbaric and hypobaric pressures. Clinical and subclinical decompression sickness was produced. No clinical, radiologic, or post-mortem evidence of osteonecrosis was discovered during either the 6-month pressure exposure or the 13-month observation period that followed.
APPROVED FOR PUBLIC RELEASE