Accession Number:

ADA021287

Title:

Evaluation of the Squirrel Monkey (Saimiri sciureus) as an Experimental Animal Model for Dysbaric Osteonecrosis.

Descriptive Note:

Final rept.,

Corporate Author:

NAVAL AEROSPACE MEDICAL RESEARCH LAB PENSACOLA FL

Personal Author(s):

• Kupper, James L.

Report Date:

1976-01-07

Pagination or Media Count:

12.0

Abstract:

In an attempt to develop an animal model for dysbaric ostenonecrosis in man, squirrel monkeys were repeatedly exposed to a profile consisting of both hyperbaric and hypobaric pressures. Clinical and subclinical decompression sickness was produced. No clinical, radiologic, or post-mortem evidence of osteonecrosis was discovered during either the 6-month pressure exposure or the 13-month observation period that followed.

Descriptors:

• *DECOMPRESSION SICKNESS
• *SQUIRREL MONKEYS
• EXPERIMENTAL DATA
• MODELS
• HYPOBARIC CONDITIONS
• LABORATORY ANIMALS
• HYPERBARIC CONDITIONS
• MUSCULOSKELETAL DISEASES

Subject Categories:

• Stress Physiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE