Accession Number:

ADA019922

Title:

Body Fluid Distribution in Acute Hypercapnia

Descriptive Note:

Interim rept.

Corporate Author:

NAVAL SUBMARINE MEDICAL RESEARCH LAB GROTON CT

Report Date:

1975-06-16

Pagination or Media Count:

16.0

Abstract:

Guinea pigs and rats were exposed to 1.9, 6.9 and 10.8 CO2 for a period of one hour. Measurements of total body water TBW, extracellular fluid ECF and intracellular fluid ICF were made using tritiated water and radioactive chloride Cl36. Control values for TBW, ECF and ICF were 64.6, 28.5 and 36.1 for rats and 61.7, 30.6 and 31.1 for guinea pigs. These values did not change significantly under hypercapin. These results indicate that although no measurable changes occurred in body fluid distribution under hypercapnia, the differences in body water distribution between guinea pigs and rats may help explain species differences in response to hypercapnic stress.

Subject Categories:

  • Stress Physiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE