Accession Number:

ADA014524

Title:

Skin Hypersensitivity of Guinea Pigs with Plague Immunity to Different Pestin PP Fractions,

Descriptive Note:

Corporate Author:

FOREIGN TECHNOLOGY DIV WRIGHT-PATTERSON AFB OHIO

Report Date:

1975-06-19

Pagination or Media Count:

14.0

Abstract:

The effectiveness of pestin PP and its components, obtained with Sephadex G-50, has been compared to detect the skin hypersensitivity response in guinea pigs given one immunizing dose of live P. pestis YeV or infected by a virulent strain after vaccination. Component I the polypeptide-polysaccharide complex and its fragment Ia, having the specificity of the basic somatic antigen, caused the most demonstrative cutaneous response.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE