Skin Hypersensitivity of Guinea Pigs with Plague Immunity to Different Pestin PP Fractions,
FOREIGN TECHNOLOGY DIV WRIGHT-PATTERSON AFB OHIO
Pagination or Media Count:
The effectiveness of pestin PP and its components, obtained with Sephadex G-50, has been compared to detect the skin hypersensitivity response in guinea pigs given one immunizing dose of live P. pestis YeV or infected by a virulent strain after vaccination. Component I the polypeptide-polysaccharide complex and its fragment Ia, having the specificity of the basic somatic antigen, caused the most demonstrative cutaneous response.
- Medicine and Medical Research