Accession Number:

ADA014271

Title:

Synthesis of Antimalarial C-Nucleosides.

Descriptive Note:

Rept. no. 8 (Final),

Corporate Author:

MICHIGAN TECHNOLOGICAL UNIV HOUGHTON

Personal Author(s):

Report Date:

1975-01-31

Pagination or Media Count:

66.0

Abstract:

Approximately 80 compounds have been submitted to WRAIR for screening against malaria. The compounds synthesized include C-analogs of the antibiotics cordycepin, puromycin and Ara-A as well as C-analogs of adenosine and its derivative. The compounds screened by the Schizonticidal test using ICRHA Swiss mice were inactive.

Subject Categories:

  • Pharmacology
  • Organic Chemistry

Distribution Statement:

APPROVED FOR PUBLIC RELEASE