Accession Number:

ADA013854

Title:

Neural Integration in Learning and Memory: A Hypothesis

Descriptive Note:

Corporate Author:

FEDERATION OF AMERICAN SOCIETIES FOR EXPERIMENTAL BIOLOGY BETHESDA MD LIFE SCIENCES RESEARCH OFFICE

Personal Author(s):

• Bach, Sven A.

Report Date:

1975-04-01

Pagination or Media Count:

37.0

Abstract:

Presented is a hypothesis concerning neural integration in learning and memory based on biochemical events in this time domain. The hypothesis suggests that one of the events involved in intraneuronal message transfer may be pumping of lattice-vibrational states by signals pulsed to match the relaxation time of such states. The energy levels attainable can in turn match those required for conformational changes in macromolecules. Intracellular processes may play an equal or larger role in neural functioning than events measurable across the cell-membrane. The hypothesis provides a basis for study of early, time-variable concentrations of metabolic intermediates, metabolites and secretory products of neurons during memory and learning.

Descriptors:

• *LEARNING
• *MEMORY(PSYCHOLOGY)
• *NERVE CELLS
• *NEUROCHEMISTRY
• BIOCHEMISTRY
• BIOLOGICAL RHYTHMS
• BRAIN
• HYPOTHESES
• METABOLISM
• METABOLITES
• PSYCHOPHYSIOLOGY

Subject Categories:

• Psychology
• Biochemistry
• Anatomy and Physiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE