Accession Number:

ADA011873

Title:

Pulmonary Changes Induced by Ambient Levels of Ozone. A Morphological Study.

Descriptive Note:

Final rept.,

Corporate Author:

AEROSPACE MEDICAL RESEARCH LAB WRIGHT-PATTERSON AFB OHIO

Report Date:

1974-12-01

Pagination or Media Count:

18.0

Abstract:

The objectives were to define the lesions of ambient levels of O3 0.2, 0.5, and 0.8 ppm after seven days of intermittent exposure using light microscopy, scanning electron microscopy SEM, and transmission electron microscopy TEM. SEM provided the advantages of observing large tissue samples and correlation of surface alterations with histologic and ultrastructural changes. This study was part of a larger one designed to correlate biochemical and morphological findings following O3 exposure and to compare the effects of continuous and intermittent daily exposure regimes. A portion of the biochemical results and the histochemical results have been published previously Castleman et al., 1973a Castleman et al., 1973b Chow et al., 1974.

Subject Categories:

  • Toxicology
  • Air Pollution and Control

Distribution Statement:

APPROVED FOR PUBLIC RELEASE