Accession Number:

ADA011859

Title:

Cardiac Sensitization Studies in Dogs with Myocardial Infarctions.

Descriptive Note:

Final rept.,

Corporate Author:

AEROSPACE MEDICAL RESEARCH LAB WRIGHT-PATTERSON AFB OHIO

Report Date:

1974-12-01

Pagination or Media Count:

16.0

Abstract:

In man, myocardial infarction is the most serious form of ischemic cardiovascular disease and, because of its frequent occurrence, it is the single most important type of heart disease. Since myocardial infarction is common in the human population, the authors attempted to determine whether such a condition might place an individual, exposed to high halocarbon concentrations, at greater risk from an epinephrine-induced cardiac arrhythmia. Such exposure conditions could occur in the chemical industry, or in the refrigeration and aerosol industries. Using the dog as an animal model for myocardial infarction, results imply that such an individual, having recovered from myocardial infarction and able to return to work, may be at no greater risk from cardiac sensitization than the normal healthy individual.

Subject Categories:

  • Civil Engineering
  • Environmental Health and Safety

Distribution Statement:

APPROVED FOR PUBLIC RELEASE