Accession Number:

ADA011579

Title:

The Development of a Biological Test System for Calibrating and Evaluating the Performance of Computer-Controlled Optical Scanners

Descriptive Note:

Annual rept. no. 1, 1972-1973

Corporate Author:

NEW ENGLAND MEDICAL CENTER HOSPITAL BOSTON MA

Report Date:

1975-03-01

Pagination or Media Count:

14.0

Abstract:

A method was developed for processing human red blood cells RBCs for microstereology analysis of major cell dimensions. Using this preparative method, RBCs from five normal human donors were prepared for thin section electron microscopy. A test film containing 250 electron micrographs of human RBCs was prepared and analyzed by microstereology methods. Using these methods, the calculated RBC mean corpuscular volume MCV is 79.6 cubic micrometers and the mean RBC surface area is 130.1 square micrometers. These results are consistent with results obtained by other quantitative microscopy techniques. The film is of high quality and preliminary testing indicates that the film is suitable for use in evaluations of computer soft ware that is designed to control computer-controlled optical scanners that are utilized for boundary tracing in biological materials.

Subject Categories:

  • Anatomy and Physiology
  • Medical Facilities, Equipment and Supplies

Distribution Statement:

APPROVED FOR PUBLIC RELEASE