Accession Number:

ADA011578

Title:

Unilateral Sensory-Motor-Rhythm (SMR) Training in Cats: A Basis for Testing Neurophysiological and Behavioral Effects of Monomethylhydrazine (MMH)

Descriptive Note:

Final rept. 1 Apr 1972-31 Mar 1973

Corporate Author:

CALIFORNIA UNIV LOS ANGELES SCHOOL OF MEDICINE

Personal Author(s):

Report Date:

1974-07-01

Pagination or Media Count:

22.0

Abstract:

Cats were trained to produce sensory-motor rhythm SMR in one brain hemisphere and to suppress it in the contralateral hemisphere. Rewarding brain stimulation was delivered automatically to the lateral hypothalamus when trains of SMR of specified duration and amplitude appeared only in the trained hemisphere. Evoked potentials induced bilaterally in the sensory-motor cortex by stimulation of radiations from the nucleus ventralis posteriolateralis of the thalamus were photographed and measured prior to, during, and following training. Unilateral SMR production could be achieved, but this training procedure had no systematic effect on thalamocortical evoked potentials although changes unique to each of the three animals tested occurred more frequently in the trained hemisphere.

Subject Categories:

  • Anatomy and Physiology
  • Toxicology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE