Accession Number:

ADA011450

Title:

Gastric Secretory Response to Acute Isotonic Hypervolemia.

Descriptive Note:

Medical research progress rept.,

Corporate Author:

NAVAL MEDICAL RESEARCH INST BETHESDA MD

Report Date:

1974-01-01

Pagination or Media Count:

6.0

Abstract:

The effects of acute isotonic extracellular fluid volume expansion were studied in conditioned, anesthetized dogs who underwent pyloric ligation and creation of an external gastric fistula. A hypervolemic state was produced with intravenous Ringers lactate solution. The canine stomach responded as a third-kidney by significantly increasing gastric juice volume 528 per cent and gastric acid output 696 per cent. This occurred paradoxically in the presence of a lactate load and a metabolic alkalosis.

Subject Categories:

  • Anatomy and Physiology
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE