Accession Number:

ADA010137

Title:

Coexistence of Several Putative Neurotransmitters in Single Identified Neurons of 'Aplysia'

Descriptive Note:

Scientific rept.

Corporate Author:

ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD

Personal Author(s):

• Brownstein, M. J.
• Saavedra, J. M.
• Axelrod, J.
• Zeman, G. H.
• Carpenter, D. O.

Report Date:

1974-11-01

Pagination or Media Count:

20.0

Abstract:

Recently very sensitive enzymatic assays have been developed for several neurotransmitters and putative transmitters which make it possible to assay these substances in single nerve cells of Aplysia. The authors have measured the concentrations of 5-HT, histamine, octopamine, dopamine and norepinephrine in the large identified cells from the various ganglia. In this communication studies are reported on four neurons R2, R14, L11 and C1. These neurons and others have been found to contain more than one putative neurotransmitter.

Descriptors:

• *NERVE CELLS
• *NEUROCHEMISTRY
• ACETYLCHOLINE
• AMINES
• ASSAYING
• BIOCHEMISTRY
• ENZYMES
• GLUTAMINE
• HISTAMINE
• SEROTONIN

Subject Categories:

• Biochemistry
• Anatomy and Physiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE