Study of Electrical Potential Methods for the Nondestructive Evaluation of Peripheral Nerve Regeneration.
GEOSCIENCE LTD SOLANA BEACH CALIF
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Repair of peripheral nerve injuries in human patients is important in both civilian and military practices because such injuries are the frequent result of combat or accident. Improved methods for the nondestructive examination of the regeneration process are currently needed both by research investigators and by clinicians. A literature survey was made of possible research methods that might be used to evaluate peripheral nerve regeneration on a nondestructive basis for clinical application. The nerve action potential NAP method was found to be by far the most promising. The proposed monitoring methods involve the permanent implantation of electrodes piercing the epineurium of the peripheral nerve on both the proximal and distal sides of the injured section. Two specific electrical methods are proposed. One is the nerve action potential approach where amplitudes and conduction velocities are measured. The second method involves the measurement of the electrical impedance of the regenerating nerve.
- Anatomy and Physiology