Annual Research Report 1 July 1973 -- 30 June 1974
Technical Report,01 Jul 1973,30 Jun 1974
ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD BETHESDA United States
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The objective of this research was to measure and determine the physiological and metabolic pathways of cyclotrimethylenetrinitramine RDX following oral, intraperitoneal and intravenous administration its toxic and resultant pathological effects on the various organ systems and the development of proper therapeutic and prophylactic procedures.Contents Pathophysiological studies of potentially toxic substances Biological effects of electromagnetic pulses Suppression of secondary disease by in vitro exposure of mixtures of lymphoid and stem cells to purified antilymphocyte antibody Endotoxin effects of mouse liver adenyl cyclase Development of clinical approaches for the treatment of radiation sickness and graft versus host disease through management of the intestinal flora Control of white cell population in the postirradiated animal Glycoproteins in diabetes Technetium-99m pyrophosphate--Comparison of ED50 for tetany and acidosis with acute LD50.