Accession Number:

ADA008036

Title:

Experimental Study of Wound Healing on Bone and Oral Tissue in two Experimental Animal Model Systems: Effect of Dietary Zinc, Phosphate Supplements and Calcitonin in Bone Healing.

Descriptive Note:

Final rept. Jun 60-Jul 71,

Corporate Author:

ALABAMA UNIV BIRMINGHAM INST OF DENTAL RESEARCH

Personal Author(s):

• Navia,Juan M.

Report Date:

1974-05-01

Pagination or Media Count:

109.0

Abstract:

A method to study in vivo early bone formation biochemically and histologically has been developed using the guinea pig model. Zinc supplementation at a level of 100 ppm in the diet, allowed increased deposition of calcium and phosphorus at a bone forming site. Calcitonin seems to stimulate this effect. Zinc supplementation effectively prevented the negative zinc balance that sets in immediately after a stress such as bone fracture.

Descriptors:

• *HEALING
• *DENTISTRY
• *BONE FRACTURES
• *MANDIBLE
• TISSUES(BIOLOGY)
• BIOCHEMISTRY
• ZINC
• IN VIVO ANALYSIS
• DIET
• MINERALS
• IMPLANTATION
• HISTOLOGY
• MOUTH
• PHOSPHATES
• GROWTH(PHYSIOLOGY)
• GUINEA PIGS
• CALCITONIN

Subject Categories:

• Anatomy and Physiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE