Immunochemical Study of Bovine Serum Proteins,
FOREIGN TECHNOLOGY DIV WRIGHT-PATTERSON AFB OHIO
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With the aid of immunological methods of analysis, this study characterizes certain protein fractions of the blood serum of cattle. Analyses indicate that serum proteins differ not only in their electrophoretic mobility, but also in their antigenic structure. Nevertheless, the presence of common antigenic determinants in electrophoretically heterogeneous bovine blood serum protein has been established. Among the alpha-globulins there is perhaps only one protein whose antigenic structure is identical to that of albumin. During spontaneous lysis of the transferin molecule, the presence of an internal antigenic determinant that is held in common with albumin was shown. There is also an antigenic similarity between the albumins and the gamma-globulins.