Development of a Synthetic Polymer Burn Covering.
Rept. no. 2 (Annual), 1 Feb-31 Dec 74,
DYNATECH R/D CO CAMBRIDGE MASS
Pagination or Media Count:
The quantitative in vivo evaluation of a collagenpoly-epsilon-caprolactone laminate burn covering with human cadaver skin as a reference has been carried out using the burned rat model. Insensible water loss and adherence of the covering to the excised wound have been measured. Three thicknesses 0.0005, 0.001, 0.003 inch of poly-epsilon-caprolactone PCL laminated to collagen film 0.001-0.002 inch were evaluated. The covering is grafted with the collagen towards the wound. The authors conclude that the collagenPCL laminate, can significantly reduce and control insensible water loss from a wound. However, early adherence to wound is lacking. Therefore further development of the collagen surface is required.
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