Pathogenesis, Detection, Prevention and Treatment of Infectious Diseases of Military Importance.
Annual rept. 1 Jul 73-30 Jun 74,
MARYLAND UNIV BALTIMORE SCHOOL OF MEDICINE
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The studies are aimed primarily at the evaluation of various vaccines for enteric infections of military importance. Quantitative measurements of effectiveness of oral typhoid and shigella vaccines have been carried out. In addition, attempts have been made to uncover the significance of pathogenesis of and host resistance to infection with the presumed viral agent of winter vomiting, disease, enterotoxigenic E. coli and penetrating E. coli. Availability of human models has allowed for research to explore the role of endotoxin in infectious diseases, and to attempt to define mechanisms of immunity, i.e., cellular versus humoral. The status of these studies are presented in this report.
- Medicine and Medical Research