Accession Number:

ADA002804

Title:

The Effect of Certain Antibiotics, 6-Mercaptopurine and Cortisone on the Course of Active Anaphylactic Shock in Guinea Pigs,

Descriptive Note:

Corporate Author:

FOREIGN TECHNOLOGY DIV WRIGHT-PATTERSON AFB OHIO

Personal Author(s):

• Planeles,Kh. Kh.
• Fedorov,E. I.

Report Date:

1974-11-18

Pagination or Media Count:

14.0

Abstract:

The effect of aurantin, oxytetracycline and aurantin combination with oxytetracycline as well as 6-mercaptopurine and cortisone on anaphylactic shock in guinea pigs was studied. It was found, that only cortisone used for prolong periods of time during sensitization preceded with its administration several days before sensitization protected more than 50 per cent of sensitized guinea pigs from fatal anaphylactic shock. The other preparations had no protecting effect on sensitized animals with respect to death from anaphylactic shock.

Descriptors:

• *ANTIBIOTICS
• *ANAPHYLAXIS
• USSR
• EXPERIMENTAL DATA
• SENSITIVITY
• TRANSLATIONS
• ANTIGENS
• SHOCK(PATHOLOGY)
• LABORATORY ANIMALS
• GUINEA PIGS
• CORTICOSTEROID AGENTS
• PURINES

Subject Categories:

• Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE