Accession Number:

ADA002542

Title:

Primary Irritation Evaluation Program Study.

Descriptive Note:

Final rept. Oct-Nov 74,

Corporate Author:

ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

Personal Author(s):

• Fisch,Harvey

Report Date:

1974-11-11

Pagination or Media Count:

7.0

Abstract:

1-Decanoyl-4-methylpiperazine AI3-36250-Ga, 4-6-Methyl-3-cyclohexenecarbonyl morpholine AI3-36258-Ga, 4-2-Methylcyclohexanecarbonylmorpholine AI3-36260, and 1-Decanoyl-1,3,4,6-tetrahydropyridine AI3-36307-Ga, which are insect repellents were evaluated on New Zealand White rabbits for their potential to cause skin irritation. The data obtained serve as a basis for making a recommendation concerning their potential use on humans. This recommendation is intended only for guidance in further entomological testing of these compounds.

Descriptors:

• *INSECT REPELLENTS
• *IRRITATION
• HUMANS
• TOXICITY
• CYCLOHEXANES
• EYE
• SKIN(ANATOMY)
• PYRIDINES
• CHEMICAL COMPOUNDS
• BIOASSAY
• RABBITS
• KETONES
• CYCLOHEXENES

Subject Categories:

• Toxicology
• Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE