Trypanosoma lewisi: An in vitro Model System for the Study of the Effects of Humoral Factors on Growing Parasitic Protozoa.
Final progress rept. Jul 72-Jun 74,
INDIANA STATE UNIV TERRE HAUTE DEPT OF LIFE SCIENCES
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The objectives of the investigation were to 1 characterize the antigenic components and immunologic relationships between trypanosomes of the subgenera Herpetosoma and Schizotrypanum, 2 describe antibody responses to the parasites, 3 determine the effects of homologous and heterologous antisera on the growth of the trypanosomes in vitro and 4 ascertain whether immunization with live parasites, somatic antigens and exoantigens elicits a functional immunity to Trypanosoma cruzi infection.