The Presence of Common Peptide Fragments in the Protein-Allergens of Enterobacteria,
FOREIGN TECHNOLOGY DIV WRIGHT-PATTERSON AFB OHIO
Pagination or Media Count:
The authors examined the protein-allergens isolated from the strains of a number of representatives of intestinal family -- dysentery Flexner 26. E. coli O111, typhoid No. 1203 and paratyphoid B No. 50602 by modified Tsuverkalovs method. The preparations were subjected to enzymatic splitting with crystalline trypsin, and peptide maps of hydrolyzates were obtained by the finger print method. The protein-allergens under study contained in their primary structure fragments, common by peptide composition. This circumstance was a possible cause of cross reactions seen in administration of heterologous allergens to animals sensitized with dysentery vaccine.