Accession Number:

ADA000666

Title:

The Presence of Common Peptide Fragments in the Protein-Allergens of Enterobacteria,

Descriptive Note:

Corporate Author:

FOREIGN TECHNOLOGY DIV WRIGHT-PATTERSON AFB OHIO

Personal Author(s):

Report Date:

1974-10-11

Pagination or Media Count:

13.0

Abstract:

The authors examined the protein-allergens isolated from the strains of a number of representatives of intestinal family -- dysentery Flexner 26. E. coli O111, typhoid No. 1203 and paratyphoid B No. 50602 by modified Tsuverkalovs method. The preparations were subjected to enzymatic splitting with crystalline trypsin, and peptide maps of hydrolyzates were obtained by the finger print method. The protein-allergens under study contained in their primary structure fragments, common by peptide composition. This circumstance was a possible cause of cross reactions seen in administration of heterologous allergens to animals sensitized with dysentery vaccine.

Subject Categories:

  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE