The Mechanism of Specific Desensitization by Microbe Allergens. Report I. Indices of Nonspecific Immunity in Bronchial Asthma and Change Under the Effect of Desensitization by Microbe Allergens
AIR FORCE SYSTEMS COMMAND WRIGHT-PATTERSON AFB OH WRIGHT-PATTERSON AFB
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The authors studied certain indices of immunological reactivity in patients with infectious bronchial asthma ranging in age from 16 to 60 with duration of disease from 4 months to 20 years and more. The following conclusions were drawn In bronchial asthma patients, a certain reduction in the nonspecific resistance of the organisms was manifested by a reduction in blood serum complement titer, phagocytic activity of leukocytes and phagocytic index desensitization with microbe antigens led to a certain increase in the phagocytosis indicators and complement activity of the blood and a reduction in the lysozyme titer the nature of the immunologic process, after introduction of small doses of microbe antigens over a prolonged period of time, is analogous to that found in process of immunization.