Accession Number:

ADA000359

Title:

Obtaining Bacterial Allergens by Alkaline Extraction and Research on Their Physicochemical Properties,

Descriptive Note:

Corporate Author:

FOREIGN TECHNOLOGY DIV WRIGHT-PATTERSON AFB OHIO

Personal Author(s):

Report Date:

1974-10-22

Pagination or Media Count:

16.0

Abstract:

A common method of obtaining allergens from bacteria of the group of particularly dangerous infections and of certain representatives of enteric family is suggested as a result of the work carried out. The method consists in extraction from microbial cells of alkali-soluble components, their precipitation with acid dialysis and lyophilization. The protein part of the allergens mainly contained the fraction with a high molecular weight. Thermal treatment of certain allergens tularemic and typhoid was accompanied by the rupture of bond in the protein molecule, and separation of fractions with a lesser molecular weight some retained their specific activity.

Subject Categories:

  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE