Accession Number:

AD1182855

Title:

Poincare Plot Analysis of Differences in Heart Rate Variability Between Patients with Moderate Obstructive Sleep Apnea and Without Obstructive Sleep Apnea

Descriptive Note:

[Technical Report, Master's Thesis]

Corporate Author:

UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD

Personal Author(s):

• Steigerwald, Jennifer C

Report Date:

2020-06-05

Pagination or Media Count:

72

Abstract:

Heart rate variability HRV is the variation in the interval between consecutive heart beats. This allows the cardiovascular system to respond to sudden changes in physical demands, which is required for cardiovascular balance. Obstructive sleep apnea OSA occurs when pharyngeal muscles relax during sleep causing upper airway collapse, restricting airflow. Low blood oxygenation hypoxemia is a result. Repeated hypoxemias trigger autonomic nervous system ANS imbalance, causing systemic inflammation, endothelial dysfunction and altered metabolism. The ANS has direct modulating effects on HRV. HRV is reduced in OSA patients many agree this ANS imbalance contributes to cardiovascular disease, a recognized long-term sequela of OSA. Time-domain and frequency-domain analysis of HRV can be difficult and require specialized skill. Poincar plot analysis has been proposed as a simplified alternative method. The aim of this study is to evaluate differences in HRV between patients with moderate OSA and without OSA using Poincar plots.

Descriptors:

• health services
• medical personnel
• cardiovascular physiological phenomena
• cardiovascular system
• myocardial ischemia
• cardiovascular diseases
• glucose metabolism disorders
• hypertension
• respiratory physiological phenomena
• oxygenation
• respiration disorders
• autonomic nervous system
• blood
• frequency
• metabolic diseases
• nervous system

Subject Categories:

• Anatomy and Physiology
• Medicine and Medical Research

Distribution Statement:

[A, Approved For Public Release]