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Synthesis of 2-Methoxypropyl Benzene for Epitope Imprinting

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[Technical Report, Technical Note]

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Harmful algal blooms HABs are occurring with increasing frequency and severity across the globe in part due to climate change and anthropogenic pollution Bullerjahn et al. 2016. HABs produce several classes of toxins however, microcystins MCs are the most commonly studied Lone et al. 2015 and can be potent toxins with LD50s in the range of 50 gkg Puddick et al. 2014. Sample analysis in laboratories, typically by high-pressure liquid chromatography tandem mass spectrometry HPLC-MSMS or by Enzyme Linked Immunosorbent Assays ELISAs USEPA 2015. These analytical techniques are highly sensitive and selective for the given toxins however, the time it takes to collect, transfer, prepare, and analyze a sample before the data can be reported is significant often, multiple days is the most expeditious.


Subject Categories:

  • Biology
  • Toxicology

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[A, Approved For Public Release]