Accession Number:

AD1166354

Title:

Developing Clinically Relevant Models of Mucinous Ovarian Carcinoma for Testing Therapies

Descriptive Note:

[Technical Report, Annual Report]

Corporate Author:

University of Melbourne

Personal Author(s):

• Gorringe, Kylie

Report Date:

2021-10-01

Pagination or Media Count:

10

Abstract:

This project aims to create patient-relevant models for mucinous ovarian cancer MOC. Over the last year, we have begun PDX experiments, transplanting one MOC case subcutaneously no growth after 6 months, intraperitoneally growth observed within 2 months and intrabursally growth observed within 2 months. We continue to collect tissue, although the pace has slowed, likely due to COVID disruptions at two collection sites. Nonetheless we have received four new carcinomas and one borderline tumour in the last year. Two of the carcinomas have grown sustainably as organoid lines. No cell lines have yet been able to be derived.

Descriptors:

• students
• biomedical research
• medical personnel
• cell line
• ovarian cancer
• department of defense
• neoplasms
• cancer
• australia
• cells
• computer communications
• electronic mail
• internet
• monitoring
• new zealand
• organoids
• patent applications

Subject Categories:

• Anatomy and Physiology
• Medicine and Medical Research

Distribution Statement:

[A, Approved For Public Release]