Accession Number:
AD1158214
Title:
Multimodal Intervention Trial for Cognitive Deficits in Neurofibromatosis Type 1: Efficacy of Computerized Cognitive Training and Stimulant Medication
Descriptive Note:
[Technical Report, Final Report]
Corporate Author:
CHILDRENS NATIONAL MEDICAL CTR WASHINGTON DC
Personal Author(s):
Report Date:
2021-12-01
Pagination or Media Count:
14
Abstract:
Children with NF1 demonstrate working memory difficulties which impacts cognitive and academic functioning. One hundred and three children with NF1, age 8-16 years M 11.37 years, SD 2.21 at four participating sites 50.5 percent Male, 78.6 percent Not HispanicLatino, 68.0 percent White, 14.6 percent on stimulant medication, were screened using a battery of neurocognitive tests and parent-completed questionnaires. The intervention phase included 82 children who were stratified by stimulant medication use and randomized equally between two interventions CogmedRM n 41, or the active control, MobyMax, an online reading program n 41. Children who completed CogmedRM did not outperform children who completed MobyMax but demonstrated improvement on digit span backward and spatial span forward. This computerized, home-based working memory training program was acceptable, feasible, and enjoyable for children and adolescents with NF1.
Subject Categories:
- Medicine and Medical Research
- Genetic Engineering and Molecular Biology
- Psychology