Accession Number:



TRACK-TBI Precision Medicine - Pathomechanistic Classification of Traumatic Brain Injury: The Bridge to Targeted Therapies

Descriptive Note:

[Technical Report, Annual Report]

Corporate Author:

University of California, San Francisco

Report Date:


Pagination or Media Count:



TRACK-TBI Precision Medicine utilizes the rich TRACK-TBI dataset to validate biomarkers of diffuse axonal injury DAI, microvascular injury MVI, and neuro-inflammation using advanced blood-based assay platforms and MRI sequences. The project will validate early and ultra-early blood-based and imaging biomarkers of DAI, MVI, and neuro-inflammation and will conduct a multicenter, double-blind, placebo-controlled exploratory clinical trial comparing the impact of cyclosporine A on blood-based and imaging biomarkers of DAI and neuro-inflammation in moderatesevere TBI patients.

Subject Categories:

  • Medicine and Medical Research
  • Anatomy and Physiology
  • Biochemistry

Distribution Statement:

[A, Approved For Public Release]