Accession Number:



Using Multimodal Imaging to Examine the Neural Mechanisms of an Integrative Exercise Program for Individuals with Dementia

Descriptive Note:

[Technical Report, Annual Report]

Corporate Author:

Northern California Institute for Research and Education (NCIRE)

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The goal of this project is to investigate whether participation in the Preventing Loss of Independence through Exercise PLI program for 3 months will result in neurobiological changes that improve cognitive function, leading to improvements in physical function and quality of lifeQOL. We will estimate the impact of PLI on brain atrophy rates, Default Mode Network DMNfunctional connectivity, and cerebral perfusion and determine if improvements in cognition, function, and QOL are associated with changes in brain volume, DMN functional connectivity, and cerebral perfusion in individuals who participated in PLI.


Subject Categories:

  • Medicine and Medical Research
  • Psychology

Distribution Statement:

[A, Approved For Public Release]