Accession Number:

AD1112835

Title:

Market Potential for Perfluorocarbon Based Formulations for Use in Pressurized Metered Dosed Inhalers for Pulmonary Drug Delivery

Descriptive Note:

Technical Report,28 Sep 2017,30 Jun 2019

Corporate Author:

University of Colorado - Health Science Center Aurora United States

Personal Author(s):

• Meyers,Arlen D.
• Pak,David I.
• Irwin,David C.
• Schroeder,Thies D.

Report Date:

2020-04-24

Pagination or Media Count:

13.0

Abstract:

The overarching goal of the SEMPer Fi saving lives with emergency medical perfluorcarbons program is to develop and commercialize aerosolized therapeutic formulations, based on perfluorocarbon PFC chemistry. Advanced development of these formulations are meant to bridge a technology gap that will allow pharmaceutical hydrophilic compounds to be delivered directly to the lungs via a pressurized metered dose inhaler pMDI. For the military this technology will provide a faster and more efficacious means to target the Hypoxic Pulmonary Vasoconstrictive HPV response, which hinders physical and mental performance of military personnel working in hypoxic environments.

Descriptors:

• cerebral hypoxia
• nebulizers and vaporizers
• altitude
• health care
• lung diseases
• therapy
• pulmonary hypertension
• fibrosis

Subject Categories:

• Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE