Development and Testing of New Noninvasive Monitoring Tools for Prolonged Field Care Goal-Directed Therapy
Technical Report,01 Apr 2019,31 Mar 2020
University of Michigan Ann Arbor United States
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Management of the polytrauma patient with or without TBI in the prolonged field care PFC setting especially when prolonged damage control resuscitation pDCR is required represents an extraordinary challenge. While there is a desire to develop new therapeutic agents to improve survival and mitigate tissue injury and organ failure, we have not yet developed tools which assist in helping providers maximize use of supportive treatments such blood transfusion, volume expansion, vasopressor use, etc. in a precision manner for goal directed therapy GDT. The use of goal GDT has been demonstrated to be life saving for both surgical and medical populations with severe hemodynamic compromise but is difficult to implement with current invasive and noninvasive tools because of their lack of precision or form factor and expense. This proposal will scale testing of two novel noninvasive measures that could allow for real-time use of GDT in the PFCpDCR setting.
- Medicine and Medical Research