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DoD COVID-19 Practice Management Guide: Clinical Management of COVID-19

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Technical Report

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Defense Health Agency Falls Church United States

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Coronavirus disease 2019 COVID-19 is a respiratory illness caused by a novel coronavirus SARS-CoV-2. COVID-19 was first described in Wuhan, China in December 2019 and is now a global pandemic with more than five million confirmed cases worldwide. Most 80 of those affected have milder illness, 15 will be severely ill most often some degree of hypoxemic respiratory failure and 5 will require critical care interventions. Of those who are critically ill, most require early intubation and mechanical ventilation. Other complications include septic shock and multi-organ failure, including acute kidney injury and cardiac injury, in the setting of an inflammatory and prothrombotic state. Older age and comorbid conditions, including hypertension, diabetes, and coronary artery disease increase risk of death. The virus is highly contagious and spread via respiratory droplets, direct contact, and if aerosolized, airborne routes. The intent of this publication is to provide clinicians and military medical treatment facilities MTFs with best practices based on latest evidence to optimize DoD response to the current COVID-19 pandemic.

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