Accession Number:

AD1095816

Title:

Novel Diffusion-Weighted MRI for High-Grade Prostate Cancer Detection

Descriptive Note:

Technical Report,15 Sep 2017,14 Sep 2018

Corporate Author:

University of Illinois at Chicago Chicago United States

Report Date:

2018-10-01

Pagination or Media Count:

23.0

Abstract:

Our initial findings illustrate the potential of the stretched exponential model parameters to better characterize high-grade prostate cancer. Additional work is underway to establish the correspondence between the DDC and a-maps with histological sections of the entire prostate gland. Given the technical difficulty with comparison of radical prostatectomy histology with imaging, we have also introduced a method to evaluate the accuracy of our novel diffusion imaging with biopsy histology. Development of a non-invasive quantitative imaging biomarker for high grade PCa will be useful for improving biopsy yield and grade accuracy, accurately identifying men appropriate for surveillance versus curative therapy, and reduce biopsies needed.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE