Accession Number:

AD1095757

Title:

Analgesics in the Pre-Hospital Setting: Implications on Hemorrhage Tolerance

Descriptive Note:

Technical Report,01 Jun 2018,31 May 2019

Corporate Author:

University of Texas Southwestern Medical Center Dallas United States

Personal Author(s):

Report Date:

2019-06-01

Pagination or Media Count:

10.0

Abstract:

To date our findings demonstrate mean tolerance to a simulated hemorrhagic challenge is not different between when subjects received ketamine and placebo. However, variability in the responses were high in the male subjects, with some subjects showing rather profound reductions in tolerance with ketamine while others showed improvements in tolerance with ketamine. In contrast, responses in females were more homogeneous between ketamine and placebo trials. Future work is warranted to identify sex-related differences in the obtained findings.

Subject Categories:

  • Medicine and Medical Research
  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE