Employing Tissue Oxygen Delivery Calculations to Predict Aeromedical Evacuation Patient Outcomes---A Pilot Study
Technical Report,01 Mar 2014,30 Jun 2019
AIR FORCE RESEARCH LAB WRIGHT PATTERSON AFB OH HUMAN PERFORMANCE WING (711TH) WRIGHT PATTERSON AFB United States
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In late 2006early 2007, the notion of tissue oxygen delivery DO2 was introduced into the aeromedical evacuation AE arena. This so-called DO2 paradigm offered up a coherent approach for Theater Validating Flight Surgeons TVFS prescribing supplemental oxygen, transfusions, and cabin altitude restriction CAR. Research into CAR suggested superior post flight outcomes, which, in turn, suggested that good DO2 7.3 ml O2kgmin might be a contributing factor. Using data obtained from a retrospective case-control study where a random sample of 50 CAR patients were matched with 50 Non-CAR patients, the DO2-GUI calculated DO2. Independent variables were DO2 and CAR status with postflight procedures, the dependent variable. While the case-control study demonstrated that CAR was associated with significantly fewer postflight procedures, this pilot study likewise found that good DO2 was associated with significantly fewer postflight procedures p 0.002. Additionally, DO2 and the number of postflight procedures exhibited a significant dose-response, inverse relationship p 0.045. As DO2 rose, the number of postflight procedures fell.
- Escape, Rescue and Survival
- Medicine and Medical Research