Accession Number:

AD1094615

Title:

The Effect of Hypobaria on Muscle Inflammation and Regeneration After Injury and Hemorrhagic Shock

Descriptive Note:

Technical Report,20 Jul 2018,19 Jul 2019

Corporate Author:

University of Nevada Las Vegas Las Vegas United States

Personal Author(s):

Report Date:

2019-08-01

Pagination or Media Count:

46.0

Abstract:

The purpose of this research is to understand the effect of long-distance flying on recovery after muscle injury and significant bleeding. This situation may affect recovery following combat injuries, especially if wounded service members are traveling from Asia to the United States. The hypothesis, there will be no difference in well-being and white blood cells populations in skeletal muscle between male mice exposed to hypobaria for 16 hours and male mice exposed to normobaria, was supported. In addition, several procedures involved in comparing the effects of two types of resuscitative fluids on muscle recovery and widespread inflammation after significant bleeding were completed. We began procedures to test the hypothesis that long-distance flying at 24 hours after muscle injury and significant bleeding will lead to slower muscle recovery.

Subject Categories:

  • Anatomy and Physiology
  • Biochemistry
  • Escape, Rescue and Survival

Distribution Statement:

APPROVED FOR PUBLIC RELEASE