Effectiveness of Trauma Management Therapy and Prolonged Exposure Therapy for the Treatment of Post Traumatic Stress Disorder in an Active Duty Sample: A Comparison Study
Technical Report,16 May 2018,15 May 2019
University of Central Florida Orlando United States
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This study will provide an evaluation of performance and suitability of the compressed versions of exposure psychotherapy to support the capability gap for the treatment of active duty service members and veterans with PTSD by comparing different exposure psychotherapy modalities. The overall objective of this study is to determine if compressed psychotherapy can be used as an effective alternative treatment for PTSD and to compare the impact of TMT and PE on social, familial, and occupational impairment. The primary objectives will be to compare 1 3-week TMT with 12-week PE and 2 3-week TMT with 2-week PE for the effectiveness of reducing PTSD symptoms. Outcomes will be determined based upon self-report and clinician ratings, as well as other aspects of psychopathology, and socialemotional functioning. The addition of the TMT group component will be assessed to determine its impact on social, familial, and occupational impairment. Blood samples will be collected from participants at baseline, post-treatment, and 3-and 6-month post assessments to identify PTSD biomarkers, e.g. predictors of response, biological subtypes of PTSD, and therapeutic markers. Collection, storage, and transfer of the blood samples to DoD will be performed according to standardized protocols provided by the DoD. Site visits will occur on a quarterly basis to assess adherence to standardized protocols.