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The Comparative Efficacy of the Masquelet Versus Titanium Mesh Cage Reconstruction Techniques for the Treatment of Large Long Bone Deficiencies

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Technical Report,30 Sep 2017,29 Sep 2018

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The University of Texas Medical Branch Galveston United States

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The study comprises a single center, randomized, two-arm clinical trial conducted at the Department of Orthopaedic Surgery and Rehabilitation, The University of Texas Medical Branch at Galveston, Texas, with a primary objective to assess and compare the functional outcomes of patients with large segmental bone defects reconstructed with the Masquelet technique MT versus the titanium mesh cage technique TMCT in combination with bone grating. The secondary objectives include the radiographic determination of defect healing, and comparative assessment of cost and resource expenditures between the two techniques. From 25 patients with segmental defects presented to our institution throughout the entire trial period, 16 met the study eligibility criteria and were successfully enrolled, and they include 9 MT, 7 TMCT. Within the last 12-month study period encompassing this report, 2 patients completed the study 1 MT and 1 TMCT, and 7 patients are still participating. These 7 study participating subjects 4 MT, 3 TMCT are being followed, and their study courses are uneventful. There was 1 potentially eligible study patient identified, however, ultimately, he was concluded not meeting the study inclusion criteria. The trial is ongoing and patient enrollment is still in progress.

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  • Medicine and Medical Research

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